B-Cell Therapies in Relapsing Remitting and Primary Progressive Multiple Sclerosis: A Short Clinical Review
نویسندگان
چکیده
The history of multiple sclerosis (MS) has been focused primarily on T cells. Nevertheless, T lymphocytes directed approaches miss to understand the complexity underlying the progressive disease. Novel evidences triggered both laboratory and clinical research in an attempt to pursue this possible mechanism of action and improve therapeutic options for patients with MS. For several years, there have been hints that B cells play an important role in MS pathophysiology, but only recently has interest increased in the role of B cell-directed therapies in MS.
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